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Clinical Efficacy and Change of Life Quality Through Using the Comprehensive Behavioral Intervention Treatment for Tics

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Fudan University

Status

Withdrawn

Conditions

Tic Disorders

Treatments

Behavioral: comprehensive behavioral intervention therapy (CBIT)
Drug: Aripiprazole 5Mg Oral Tablet

Study type

Interventional

Funder types

Other

Identifiers

NCT04765085
Sunjinhua

Details and patient eligibility

About

Study on the clinical efficacy and change of life quality through using the Comprehensive Behavioral Intervention Treatment for Tics (CBIT)

Full description

This study tried to explore the clinical effect of comprehensive behavioral intervention therapy (CBIT) on tic symptoms and the effect of improving the quality of life in children with tic disorders;explore the optimal treatment plan for tic disorder by comparing the clinical efficacy of CBIT therapy, drug therapy, and psychosocial education; explore the feasibility of using quality of life as an evaluation index for functional recovery after tic disorder treatment;

Sex

All

Ages

9 to 16 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Meets the diagnostic criteria for chronic tic disorder or Tourette syndrome (TS) according to the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V), and has been diagnosed by two pediatric psychiatrists who are associate chief physicians or more;
  • The age ranged from 9 to 16 years old;
  • The total score of tic symptoms in the Yale global Tic Severity Scale (YGTSS) is 13-30;
  • Childrens Webster's Intelligence Scale ≥ 85
  • Co-morbid ADHD, but the drug treatment dose for ADHD is stable (the drug has been stabilized for more than 6 weeks), or no drug has been taken at the beginning and during the stud

Exclusion criteria

  • There are brain organic diseases, metabolic diseases, psychiatric disorders, drug-induced involuntary movement and other extrapyramidal lesions;
  • Habit reversal training and other behavioral treatments for more than 4 weeks;
  • unwilling participants or disobedient subgroups in the study

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

0 participants in 2 patient groups

CBIT Group
Experimental group
Description:
Patients in this group would only receive the CBIT treatment.
Treatment:
Behavioral: comprehensive behavioral intervention therapy (CBIT)
Drug therapy Group
Experimental group
Description:
Patients in this group would only receive the drug therapy.
Treatment:
Drug: Aripiprazole 5Mg Oral Tablet

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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