Clinical Efficacy of In-situ Thrombolysis in Case of Intraventricular Haemorraghia by Aneurysm Rupture

Centre Hospitalier Universitaire de Nice

Status and phase: Completed; Phase 3; Phase 2

Conditions: Subarachnoid Hemorrhage; Aneurysm, Ruptured

Treatments: Procedure: fibrinolysis in situ; Procedure: drainage

Study type: Interventional

Funder types: Other

Identifiers

NCT00823485

05-CIR-03

Details and patient eligibility

About

The purpose of this study is to determine the impact of in situ fibrinolysis on the mortality at 30 days in case of subarachnoid hemorrhage.

Enrollment: 19 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• subarachnoid hemorrhage by aneurysm rupture
• severe intraventricular hemorraghia

Exclusion criteria

• pregnant women
• hemostasis disturbance

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Single Blind

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19 participants in 2 patient groups

2

Active Comparator group

Description:

drainage of hemorraghia

Treatment:

Procedure: drainage

1

Experimental group

Description:

Actylise

Treatment:

Procedure: fibrinolysis in situ