Clinical Efficacy of Using Bioactive Desensitizer Gel

Cairo University (CU)

Status: Completed

Conditions: Dentin Desensitizing Agents; Dentin Hypersensitivity; Dentin Hypersensitivity, Non-carious Cervical Lesions

Treatments: Procedure: Treatment

Study type: Interventional

Funder types: Other

Identifiers

NCT07323693

Cons 25/4

Details and patient eligibility

About

To evaluate and compare the clinical effectiveness of a Bioactive Desensitizer Gel (which releases calcium and phosphate to form hydroxyapatite) versus a standard 5% Sodium Fluoride (NaF) Varnish in reducing cervical dentin hypersensitivity (CDH) in adult patients over a period of 6 months.

Enrollment: 30 patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• • With ≥1 sensitive tooth and with exposed dentin in the upper or lower dental arches.

  • Grade IV gingival recession.
  • Schiff sensitivity score needed to be ≥2, indicating that application of a jet of air makes the patient respond and move or requests discontinuation of the stimuli application.

Exclusion criteria

• • Domestic or in-office fluoride application and bleaching 6 months before beginning of treatment

  • Long-term use of anti-inflammatory, analgesic and psychotropic drugs.
  • Allergies to product ingredients
  • Eating disorders, systemic conditions that cause or predispose patients to develop dentin hypersensitivity (for example, gastroesophageal reflux disease, GERD)
  • Excessive dietary or environmental exposure to acids.
  • Orthodontic appliance treatment within the previous three months.
  • Periodontal surgery within the previous three months before the study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 2 patient groups

Bioactive Desenstizer

Experimental group

Description:

A micro-brush applicator was saturated with the material (Predicta Bioactive Desensitizer Gel) and massaged it into the tooth for 30-40 secs.Using a rubbing motion was used to liquefy the gel and allow it to penetrate the surface

Treatment:

Procedure: Treatment

Procedure: Treatment

sodium fluoride varnish

Active Comparator group

Treatment:

Procedure: Treatment

Procedure: Treatment