Clinical Evaluation and Assesment of Ginigivitis Patients Treated by Yarrow Natural Extract in Compare to a Contro Group

Deraya University

Status and phase: Completed; Phase 1

Conditions: Gingivitis

Treatments: Drug: Yarrow and moringa mixture

Study type: Interventional

Funder types: Other

Identifiers

NCT06070571

3/23

Details and patient eligibility

About

A double-blind, prospective, randomized, intra-individual comparative, single-center clinical study was conducted. Participants were placed in parallel groups, and the study was performed in the Department of Operative Dentistry and Periodontology, Dental School and Hospital, Minia university to compare the antibacterial activity of yarrow Moringa herbal combinations nanoparticles in compared to Chlorhexidine as a potential treatment for gingivitis.

Enrollment: 40 patients

Sex: All

Ages: 25 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• a minimum of four natural uncrowned teeth in one quadrant present
• good general health
• can follow instructions

Exclusion criteria

• were pregnant or breastfeeding
• evidence of antibiotic use during the 4 weeks prior to the study
• were allergic to personal care/consumer products or their ingredients

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

Intervention group

Experimental group

Description:

Bucco-adhesive films with Yarrow and Moringa extract nanoparticles

Treatment:

Drug: Yarrow and moringa mixture

control group

Active Comparator group

Description:

Cholorohexiden oral gargles

Treatment:

Drug: Yarrow and moringa mixture