Clinical Evaluation of Dimethyl Sulfoxide Wet Bonding Technique

Manipal University College Malaysia

Status: Not yet enrolling

Conditions: Dimethyl Sulfoxide

Treatments: Other: DMSO; Other: Universal single bond adhesive

Study type: Interventional

Funder types: Other

Identifiers

NCT06635382

049/2023

Details and patient eligibility

About

Dimethyl sulfoxide (DMSO) wet bonding has shown promising results in several in vitro studies. However, there are a lack of clinical trials which prove the advantages of this technique. The aim of the study is to clinically assess the effect of DMSO wet bonding on composite restoration in non carious cervical lesions.

Enrollment: 68 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Two similar non carious cervical lesions (NCCLs) on the facial/labial surfaces of premolars.
• NCCLs of score 1-3 on the Smith and Knight tooth wear index.
• Favorable occlusion and teeth are in normal contact.

Exclusion criteria

• NCCLs on the lingual surface.
• Medically compromised individuals.
• Periodontally compromised teeth.
• Bruxism and visible wear facets in the posterior dentition.
• Fractured or visibly cracked premolars and canines.
• Known allergies to resin-based restorative materials.
• Presently undergoing orthodontic treatment.
• Abutment teeth for fixed or removable prostheses.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Double Blind

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68 participants in 2 patient groups

Universal single bond adhesive

Active Comparator group

Treatment:

Other: Universal single bond adhesive

DMSO application before Universal single bond adhesive

Experimental group

Treatment:

Other: Universal single bond adhesive

Other: DMSO