Clinical Evaluation of Injectable Platelet Rich Fibrin With Connective Tissue Graft for the Treatment of Deep Gingival Recession Defects.

Çukurova University

Status: Completed

Conditions: Gingival Recession

Treatments: Procedure: CAF+CTG+i-prf

Study type: Interventional

Funder types: Other

Identifiers

NCT04032405

CukurovaU-PER

Details and patient eligibility

About

Aim: The aim of this study was to determine whether the combined connective tissue graft (CTG) with injectable platelet rich fibrin (i-prf) with coronally advanced flap (CAF) improved root coverage of deep Miller Class I or II gingival recessions compared to CTG alone with CAF.

Methods: Seventy-two patients with Miller class I and II gingival recessions were enrolled. Thirty-six patients were randomly assigned to the test group (CAF+CTG+i-prf) or control group (CAF+CTG). Clinical evaluations were made at 6 months

Enrollment: 72 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ≥19 years of age,
• Periodontally and systemically healthy,
• FMPS and FMBS <15%,
• Presence of deep Miller class I and II gingival recession defect (≥3 mm in depth) at the buccal aspect of incisors,

Exclusion criteria

Smoking,

• Contraindications for surgery,
• Presence of recession defects associated with caries, deep abrasion, restoration or pulpal pathology.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

---

72 participants in 2 patient groups

CAF+CTG

Active Comparator group

Description:

the combined connective tissue graft (CTG) with coronally advanced flap (CAF)

Treatment:

Procedure: CAF+CTG+i-prf

CAF+CTG+i-prf

Experimental group

Description:

the combined connective tissue graft (CTG) and injectable platelet rich fibrin (i-prf) with coronally advanced flap (CAF)

Treatment:

Procedure: CAF+CTG+i-prf