Clinical Evaluation of Silver Nanoparticles in Comparison to Silver Diamine Fluoride in Management of Deep Carious Lesions

Suez Canal University

Status

Completed

Conditions

Caries,Dental

Treatments

Drug: silvernanoparticles

Drug: SDF

Study type

Interventional

Funder types

Other

Identifiers

NCT05231330

HR1

Details and patient eligibility

About

this clinical study will be carried out to evaluate the effect of fluoride varnish with silver nanoparticles in comparison to silver diamine fluoride in management of deep carious lesions.

Enrollment

36 patients

Sex

All

Ages

18 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

success will be evaluated by:
1. Cold pulp testing: An ice-rod will be used for this test. Results should be positive or negative.
2. Absence of spontaneous pain: Post-operative pain will be assessed using the visual Analogue Scale Score (VAS), which is a measurement method for subjective characteristics of pain. Respondents specify their level of agreement to a statement by indicating a position along a 10 cm line between two end-points, with the term "no sensitivity" at one end and "intolerable sensitivity" at the other end. A score from (0 to 10 is given).
3. Sensitivity to percussion: (presence/ absence).
4. Inspection for Sinus/fistula/swelling: using visual inspection (presence/ absence).
5. Radiographic examination: Indicating presence of periapical radiolucencies, widening of lamina dura, internal and external root resorption (presence/ absence).

Exclusion criteria

Patient-related criteria:
- Medically compromised patients, who will not be able to attend multiple appointments or may require special management.
- Pregnant women; as radiographs cannot be taken for them.
- Allergy to any of the restorative materials, including anesthetics.
- Uncooperative patients, will not abide by the instructions or attend the appointments.

Tooth related criteria:

Retained deciduous teeth; as the study is targeting only permanent teeth.
Teeth with previous restorations, which may add another variable to the study (type of old restorative material, extent of recurrent caries.
Teeth with cervical caries; which can't be evaluated on periapical radiographs