Clinical Evaluation of Two Different Surgical Techniques With PRF in the Treatment of Multiple Gingival Recessions

Pamukkale University

Status: Not yet enrolling

Conditions: Gingival Recession

Treatments: Procedure: CAF with PRF; Procedure: Tunnel with PRF

Study type: Interventional

Funder types: Other

Identifiers

NCT06986525

E-60116787-020-365617

Details and patient eligibility

About

This prospective clinical study aims to evaluate and compare the effectiveness of coronally advanced flap (CAF) and tunnel techniques, both combined with platelet-rich fibrin (PRF), in the treatment of multiple Miller Class I-II gingival recessions. Eleven participants with bilateral defects will be treated using a split-mouth design. Periodontal parameters will be assessed at baseline, 3 months, and 6 months.

Full description

The objective of this prospective clinical trial is to compare two mucogingival surgical techniques-coronally advanced flap (CAF) and tunnel technique-used in combination with platelet-rich fibrin (PRF) for treating multiple Miller Class I-II gingival recessions. Eleven systemically healthy participants with bilateral gingival recessions will be enrolled. CAF+PRF will be applied on one side, and Tunnel+PRF on the contralateral side. Clinical parameters including plaque index, gingival index, bleeding on probing, probing depth, clinical attachment level, recession height and width, and keratinized tissue height will be recorded at baseline, 3 months, and 6 months. Root coverage outcomes and clinical attachment gain will be analyzed.

Enrollment: 10 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age 18 years or older
• Systemically healthy individuals
• Presence of bilateral Miller Class I-II multiple gingival recessions
• Good oral hygiene and willingness to follow instructions
• Signed informed consent

Exclusion criteria

• Use of tobacco or smoking
• Pregnancy or lactation
• Presence of systemic diseases affecting periodontal health
• Use of medications that may affect healing (e.g., corticosteroids)
• Periodontal surgery in the same area within the last 6 months

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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10 participants in 2 patient groups

CAF + PRF

Experimental group

Description:

This group will receive coronally advanced flap (CAF) surgery combined with platelet-rich fibrin (PRF) for the treatment of multiple gingival recessions.

Treatment:

Procedure: CAF with PRF

Tunnel + PRF

Experimental group

Description:

This group will receive tunnel surgical technique combined with platelet-rich fibrin (PRF) for the treatment of multiple gingival recessions.

Treatment:

Procedure: Tunnel with PRF