Clinical Evaluation of Visual Field Change in Glaucoma: an Assessment of Different Models of Progression

Centervue

Status: Enrolling

Conditions: Glaucoma

Study type: Observational

Funder types: Industry

Identifiers

NCT05801471

CMP_005

Details and patient eligibility

About

The purpose of this observational study is to collect over time a series of data in patients with glaucoma in order to evaluate different approaches in defining the progression of this pathology. These data will be collected in repeated visits over a 36-months follow-up period. At each visit, the COMPASS fundus perimeter and the Humphrey Field Analyzer (HFA) perimeter will be used to assess retinal functionality; an Optical Coherence Tomography (OCT) examination will also be performed to evaluate and obtain clinical information about the structure of the retina.

Enrollment: 200 estimated patients

Sex: All

Ages: 40 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Glaucomatous optic nerve head in both eyes;
• Age between 40 and 90 years;
• Best Corrected Visual Acuity ≤ 0.3 [logMar];
• Spherical refraction between -6D and +6D;
• Astigmatism between -2D and +2D.

Exclusion criteria

• Any ocular surgery, except for: uncomplicated cataract surgery and/or glaucoma surgery in both eyes performed within 6 months before enrollment;
• Any ocular pathology that can affect visual field other than glaucoma;
• Use of any drug that can interfere with the correct execution of perimetry or that would produce visual field loss;
• Inability to obtain reliable perimetric examinations;
• Patients with advanced glaucoma for whom, according to the clinician, a 24-2 grid is not advisable to correctly monitor the patient.