Clinical Factors Associated With Position Sense in Patients With Multiple Sclerosis

Gazi University

Status: Completed

Conditions: Multiple Sclerosis

Treatments: Other: Assessment

Study type: Observational

Funder types: Other

Identifiers

NCT04548297

2020-122

Details and patient eligibility

About

Sensory impairment is an important problem for patients with Multiple Sclerosis (MS). Although there is no complete loss of sensation in patients, 80% of patients have a significant sensory impairment. The sensory system plays an important role in providing the feedback required to perform motor tasks. Cutaneous sensation, especially in the sole of the foot, is very important in maintaining balance and gait. There are studies showing decreased foot sole sensation in MS patients. Another sensation that is important during motor tasks is the proprioceptive sensation.

The aim of this study is to examine the relationship between the sensation of foot sole and joint position, clinical features, attention, fatigue, body awareness and physical activity level in patients with MS.

Full description

Patients with MS between 0-5,5 score according to the Extended Disability Status Scale (EDSS) and healthy individuals of similar age and sex to patients will be included in the study. The sensation of foot sole, joint position sensation, attention, fatigue, body awareness, and physical activity level will be evaluated.

The investigators will use t-tests to compare for quantitative variables and chi-square for the categorical variables between groups. In addition, the investigators will examine the correlations between the sensation of the foot sole, joint position sensation, attention, fatigue, body awareness, and physical activity level using Pearson bivariate correlations.

Enrollment: 44 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18-65 years of age
• Having a diagnosis of "Multiple Sclerosis"
• Relapse free in the last 3 mounts
• Ambulatory status (Expanded Disability Status Scale score ≤ 6 )
• No diagnosis of depression

Exclusion criteria

• Any cardiovascular, orthopedic, visual, and hearing problems that may affect the results of the research

Trial design

44 participants in 2 patient groups

Patients with Multiple Sclerosis

Description:

MS patients (EDSS: 0-5,5)

Treatment:

Other: Assessment

Healthy group

Description:

Healthy individuals without chronic disease

Treatment:

Other: Assessment