Clinical Impact of the FilmArray Blood Culture Identification Panel Performed on Positive Blood Cultures From Intensive Care Patients With Septicemia (SEPSIS2016)

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Status: Completed

Conditions: Septicemia

Treatments: Diagnostic Test: FilmArray blood culture identification panel

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT03943719

2016/19SEP/401 (Other Identifier)

SEPSIS2016

Details and patient eligibility

About

Molecular testing is a largely validated approach allowing rapid identification of positive blood cultures. However, due to its high cost and its limited information on susceptibility, it is considered as an add-on technique reserved for specific patient populations. In our study, we specifically evaluated molecular testing in a critical care setting and measured its impact on the therapeutic management of critically ill with positive blood cultures. Through the analysis of 110 positive blood culture episodes included in both pre- and post intervention period, we measured a drastic 14h-reduction of the time to administration of the optimal antimicrobial treatment with the use of the molecular approach.

Enrollment: 139 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult intensive care unit patients with positive blood cultures

Exclusion criteria

• palliative care patients