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Clinical Implications of DNA Analysis on ADPKD (DNAAA)

K

Kyorin University

Status

Completed

Conditions

Autosomal Dominant Polycystic Kidney Disease

Study type

Observational

Funder types

Other
Industry

Identifiers

NCT02322385
Kyorin-PKD-1

Details and patient eligibility

About

Autosomal dominant polycystic kidney disease (ADPKD) is an inherited disease. We plan DNA analysis using the next generation sequencer (NGS) and examine the relationship between mutational types and clinical phenotypes. The accuracy of DNA analysis with NGS is tested by Sanger's method. The kidney and life survival curves will be compared between PKD1, PKD2 and non-ADPKD family members.

Full description

80 unrelated patients with ADPKD attending to the Kyorin University Hospital whose clinical data are compiled. DNA analysis is performed at Otsuka Pharmaceutical Laboratory.

Clinical data include total kidney volume (TKV), TKV slope, eGFR, eGFR slope and other clinically relevant data.

Enrollment

80 patients

Sex

All

Ages

20 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • The unrelated patients with ADPKD.

Exclusion criteria

  • The patients whose clinical data are not compiled.

Trial contacts and locations

2

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Data sourced from clinicaltrials.gov

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