Clinical Isolation Syndrome of Spinal Cord and Multiple Sclerosis

Peking University

Status: Unknown

Conditions: Clinical Isolation Syndrome of Spinal Cord; Multiple Sclerosis

Study type: Observational

Funder types: Other

Identifiers

NCT04952246

M2020513

Details and patient eligibility

About

The purpose of this study was to investigate the factors that influence the progression of patients with clinically isolated spinal cord syndrome to multiple sclerosis.

Full description

This study included patients who were first diagnosed with clinically isolated spinal cord syndrome admitted to the Department of Neurology, Peking University Third Hospital between January 2010 and November 2020. According to the result of the outcome is divided into multiple sclerosis and outcome group, analyzing the characteristics of the age, sex, clinical manifestations, imaging features, evoked potential, blood immune antibody results, rate of cerebrospinal fluid routine biochemical synthesis oligoclonal band IgG, extension, nerve dysfunction score spinal cord clinically isolated syndrome and the influence factors, such as the relationship between the outcome of multiple sclerosis.

Enrollment: 150 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

Diagnosis time and place: Department of Neurology, Peking University Third Hospital from January 2010 to November 2020 Diagnosed as a patient with clinically isolated spinal cord syndrome for the first time

Exclusion criteria

none

Trial design

150 participants in 2 patient groups

multiple sclerosis group

non-prognosis group