Clinical Manifestations and Long-Term Outcome in Early Lyme Neuroborreliosis

University Medical Centre Ljubljana

Status: Completed

Conditions: Lyme Disease

Study type: Observational

Funder types: Other

Identifiers

NCT04653558

LNB-2020

Details and patient eligibility

About

In this retrospective cohort study of patients with early Lyme neuroborreliosis (LNB), clinical and microbiologic characteristics and long-term outcome of definite vs. possible LNB were evaluated at a single university medical center in Slovenia. Severity of acute disease and long-term outcome during a 12-month follow-up were assessed using a composite clinical score based on objective clinical findings and subjective complaints.

Enrollment: 311 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• early Lyme neuroborreliosis

Exclusion criteria

• Not fulfilling study criteria for definite or possible Lyme neuroborreliosis
• Alternative diagnosis during follow-up
• Concomitant tick-borne encephalitis
• Clinical symptoms/signs present for >6 months
• Data not available

Trial design

311 participants in 2 patient groups

definite LNB

Description:

patients with definite early Lyme neuroborreliosis

possible LNB

Description:

patients with possible early Lyme neuroborreliosis