Clinical Observation of Coronary Arterial Microcirculation Dysfunction in Diabetic Patients With Non- Obstructive Coronary Artery Disease

Shaanxi Provincial People's Hospital

Status: Unknown

Conditions: Coronary Artery Disease; Complications of Diabetes Mellitus

Study type: Observational

Funder types: Other

Identifiers

NCT02748980

LHJJ20159029

Details and patient eligibility

About

The purpose of this study is to investigate the prevalence and degree of coronary arterial microcirculaiton dysfunction of non- obstructive coronary artery disease in patients with type 2 diabetes. Furthermore, the risk factors of coronary arterial microcirulation would be screened and identified.

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis non- obstructive coronary artery disease;
• Positive Treadmill exercise test;
• Positive Cardiac ECT test;
• Positive Holter test

Exclusion criteria

• Diagnosis of myocardial infarction;
• Diagnosis heart failure;
• Diagnosis of chronic kidney disease;
• Diagnosis of heart valvular disease;
• Diagnosis of malignant tumor;
• Positive heart transplant history;
• Pregnant and lactating women

Trial design

200 participants in 2 patient groups

Non- obstructive coronary artery disease, non- diabetic

Description:

Clinical evidences such as Holter, Treadmill exercise test and cardiac ECT support myocardial ischemia. CAG showed 20%-70% arterial stenosis. Patients are diagnosed without diabetes.

Non- obstructive coronary artery disease, diabetic

Description:

Clinical evidences such as Holter, Treadmill exercise test and cardiac ECT support myocardial ischemia. CAG showed 20%-70% arterial stenosis. Patients are diagnosed with type 2 diabetes.