Clinical Observation of Exosomes in Patients After Q-switched Laser Surgery

Nanjing Medical University

Status: Enrolling

Conditions: Skin Regeneration; Exosome; Laser

Treatments: Drug: Exosome liquid dressing

Study type: Interventional

Funder types: Other

Identifiers

NCT06279039

KY20230116-06

Details and patient eligibility

About

the goal of this half-face controlled study is to evaluate the effect of exosome-containing liquid dressings on the recovery of patients after Nd:YAG laser 532 treatment.

Full description

The main objective was to collect patients with fleae or seborrheic keratosis after Q-switched laser treatment, and then to use exosomes or matrix on both sides of the face, and finally to evaluate the effect of exosomes on wound healing and prevention of post-inflammatory hyperpigmentation after Nd:YAG laser 532 treatment

Enrollment: 38 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• It meets the diagnostic criteria of seborrheic keratosis or freckle；
• pepole are able to follow the treatment rules of the study and were followed up for 8 weeks；
• informed consent

Exclusion criteria

• History of keloids ;
• Pregnancy or lactation;
• Any cosmetics containing growth factor-related ingredients used within 6 months prior to treatment
• Patients with incomplete observation data and incomplete course of treatment were excluded

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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38 participants in 1 patient group

self half face control method

Experimental group

Description:

One side of the face was treated with exosome liquid dressing twice a day, and the other side was treated without exosome matrix for 2 weeks. The patients were followed up before treatment and 1, 3，7, 14, 28, and 56 days after treatment

Treatment:

Drug: Exosome liquid dressing