Clinical Outcome Following Early Decannulation of Severe Acquired Brain Injury Patients

Rigshospitalet

Status: Active, not recruiting

Conditions: Brain Injuries

Treatments: Other: Decannulation

Study type: Observational

Funder types: Other

Identifiers

NCT06167538

p-2023-14366

Details and patient eligibility

About

After severe acquired brain injury (SABI: severe traumatic brain injury, stroke, anoxic brain damage), up to 50-70% of patients are tracheostomized. The need to tracheostomize a patient is based on the prolonged inability to breathe and/or protect their airway sufficiently. This is usually done in an Intensive Care Unit (ICU). A tracheostomy is first removed when the patient's clinical conditions allow for it. The removal can be performed in many settings, a neurological rehabilitation unit being one of these.

The overall objective of this study is to evaluate the safety of this earlier decannulation procedure in patients with SABI at our department as well as the effectiveness on functional ability.

Enrollment: 60 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

All severe acquired brain injury patients ≥ 18 years with a tracheal tube at admission.

Exclusion criteria

Trial design

60 participants in 2 patient groups

SABI patients with a tracheal tube treated with the new decannulation procedure.

Description:

All adult SABI patients ≥ 18 years with a tracheal tube at admission to the Department of Brain Injury from September 2021 to October 2022 and treated with the new decannulation procedure.

Treatment:

Other: Decannulation

SABI patients in whom decannulation was attempted before implementation of the new procedure.

Description:

Patients with SABI and a tracheal tube in whom decannulation was attempted between July 2019 until December 2020 will serve as a historical control group.

Treatment:

Other: Decannulation