Clinical Pharmacist-led Appropriate Acid Suppression Therapy Stewardship Program

Marmara University

Status: Completed

Conditions: Geriatric

Treatments: Other: Clinical Pharmacist-led Appropriate Acid Suppression Therapy Stewardship Program

Study type: Interventional

Funder types: Other

Identifiers

NCT05113667

MUHSI-2019/29-78

Details and patient eligibility

About

To evaluate the impact of clinical pharmacist-led appropriate acid suppression therapy stewardship program in hospitalized older patients.

Full description

This prospective, nonrandomized controlled study was conducted in older patients who ordered proton pump inhibitor (PPI) at admission in an internal medicine service of tertiary training and research hospital. In the intervention group, clinical pharmacist-led services (including medication reconciliation and medication review) were conducted during hospitalization and at discharge by using the guidelines and potentially inappropriate medications (PIM) criteria [American Geriatric Society-AGS Beers Criteria©, 2019]. Medication Appropriateness Index (MAI), inappropriate PPI cost, and hospitalization for gastrointestinal bleeding within 1 year after discharge were calculated in both groups

Enrollment: 250 patients

Sex: All

Ages: 65 to 95 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 65 years old or greater
• Admitted to the hospital with any reason
• Ordered at least one PPI dose within 48 hours of admission

Exclusion criteria

• Transferred to another ward (including an intensive care unit)
• Having active gastrointestinal bleeding
• Having active malignity

Trial design

Primary purpose: Health Services Research

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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250 participants in 2 patient groups

Clinical pharmacist-led services

Experimental group

Description:

Clinical Pharmacist-led Appropriate Acid Suppression Therapy Stewardship Program

Treatment:

Other: Clinical Pharmacist-led Appropriate Acid Suppression Therapy Stewardship Program

Control group

No Intervention group

Description:

Usual care