Clinical Pharmacist-led Inpatient Anticoagulation Stewardship Program

Ain Shams University

Status: Completed

Conditions: Mitral Valve Disease; Atrial Fibrillation; Deep Vein Thrombosis

Treatments: Other: Anticoagulation Stewardship Program

Study type: Interventional

Funder types: Other

Identifiers

NCT03812848

165

Details and patient eligibility

About

This study aims at evaluating the implementation of clinical-pharmacist-led anticoagulation stewardship program in Egyptian tertiary hospital to promote a culture of safety around anticoagulants.

Full description

One of the high-alert medication categories that may cause significant patient harm if not used correctly is anticoagulants. It is not clear if medication errors are more common with this category in specific compared to other medication categories, but the ramifications of a medication error with the use of anticoagulation agents is without a doubt detrimental to the patient's health and more serious than most of other drug categories.

This prospective study evaluates the impact of implementing an anticoagulation stewardship program, led by clinical pharmacists, on anticoagulation therapy outcomes during patient hospitalization by the percent of medication errors reduction, percent of adverse drug events reduction, and percent of evidence-based guidelines compliance improvement.

Enrollment: 233 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

All hospitalized patients on therapeutic anticoagulant medication during their hospitalization period.

Exclusion criteria

1. Patients whose age is less than 18 years old.
2. Patients who were admitted for less than 24 hours for patient on parenteral anticoagulants and less than 48 hours for patient on warfarin.
3. Patients already admitted for bleeding or thrombosis.
4. Malignancy patients.

Trial design

Primary purpose: Health Services Research

Allocation: Non-Randomized

Interventional model: Sequential Assignment

Masking: None (Open label)

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233 participants in 2 patient groups

Pre program implementation

No Intervention group

Description:

All hospitalized patients on therapeutic anticoagulant medication during the pre-implementation period of the anticoagulation stewardship program.

Post program implementation

Experimental group

Description:

All hospitalized patients on therapeutic anticoagulant medication during the post-implementation period of the anticoagulation stewardship program.

Treatment:

Other: Anticoagulation Stewardship Program