Clinical Phenotypes of COPD Patients Between in Plateau and Plain

Peking University

Status: Completed

Conditions: Pulmonary Disease, Chronic Obstructive

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT04964076

LM2020390

Details and patient eligibility

About

We aimed to collect clinical and radiological data of patients with stable COPD in plateau and plain, and compare the clinical phenotypic characteristics and imaging features of COPD patients in these two areas.

Full description

The purpose of this study was to investigate the clinical phenotypic characteristics and imaging features of patients with stable chronic obstructive pulmonary disease (COPD) in plateau and plain. We conducted a cross-sectional study, collecting clinical data of stable patients in plateau and plain, and comparing the clinical phenotypic characteristics and imaging features of COPD patients in these two areas.

Enrollment: 104 patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• meeting the diagnosis of COPD according to Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines and had definite airflow limitation with a post-bronchodilator forced expiratory volume in 1 second (FEV1) / forced vital capacity (FVC)<0.7.

Exclusion criteria

• age <40 years;
• subjects with airway diseases other than COPD;
• acute exacerbation of COPD in the past 3 months;
• active tuberculosis;
• cardiovascular or cerebrovascular events in the past 3 months;
• cognitive dysfunction such as vascular dementia or Alzheimer's disease;
• refusal to participate in this study.

Trial design

104 participants in 2 patient groups

COPD patients in the plateau

Description:

We consecutively enrolled COPD patients visiting the outpatient of Respiratory Medicine at Tibet Autonomous Region People's Hospital from January 2018 to December 2021.

Treatment:

Other: No intervention

COPD patients in the plain

Description:

We consecutively enrolled COPD patients visiting the outpatient of Respiratory Medicine at Peking University Third Hospital from January 2018 to December 2021.

Treatment:

Other: No intervention