Clinical, Physiological and Prognostic Implication of Microvascular Status

Seoul National University

Status

Unknown

Conditions

Coronary Artery Disease

Study type

Observational

Funder types

Other

Identifiers

NCT02186093

1404-057-573

Details and patient eligibility

About

There are several physiologic parameters in evaluating cardiovascular disease. This study will reveal which parameter is the most proper value in predicting disease severity and risk factors of patients.

Full description

Fractional Flow Reserve (FFR), index of microcirculatory resistance (IMR), and coronary flow reserve (CFR) will be measured in stable angina patients before coronary intervention.

Relationship between angiographic characteristics of patients and FFR, IMR, CFR will be analyzed. Comparison of risk factors and prognosis between parameters will be also analyzed. This study will evaluate that which parameter is correlate with disease severity and risk factors of patients.

Enrollment

1,197 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age ≥ 18
Patients with stable angina
FFR, IMR, CFR were measured before coronary intervention

Exclusion criteria

Patients who have severe side effects or contraindication to hyperemic agents (ex. adenosine)
Patients with hemodynamic instability
elevation of cardiac enzymes, evidence of acute MI, or a culprit vessel of acute coronary syndrome