Clinical Practice Guidelines Versus Decision-support for Latent Tuberculosis Infection (LTBI) Management

Johns Hopkins University

Status: Completed

Conditions: Latent Tuberculosis

Treatments: Behavioral: CDC/NTCA guidelines only; Behavioral: LTBI ASSIST and CDC/NTCA guidelines only

Study type: Interventional

Funder types: Other

Identifiers

NCT05772065

IRB00376488

Details and patient eligibility

About

Latent Tuberculosis infection (LTBI) guidelines can be complex. LTBI-ASSIST is a web-based interactive tool to navigate US LTBI clinical practice guidelines in a patient-centered format that may guide clinical decision making around Latent TB care.

The research goal is to determine the difference in reported confidence among trainees that are not experts in LTBI care. The investigators further aim to assess if access to the LTBI-ASSIST tool improves clinical decision making in a series of simulated case scenarios containing guideline-derived, multiple choice items, as well as assess the efficiency in navigating the scenarios - measured by time to complete the survey.

The investigators proposed a randomized study design, in which an electronic survey/questionnaire with 4 case scenarios consisting of 14 multiple choice questions. Participants providing informed consent will be randomized to receiving access to either US Centers for Disease Control (CDC)/National Tuberculosis (TB) Controllers Association (NTCA) Guidelines or the LTBI-ASSIST online tool. Those in the experimental arm will further complete a 10 question System Usability Scale to assess usability of the LTBI-ASSIST tool.

All Johns Hopkins medical trainees and residents will be eligible to participate.

Enrollment: 168 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Student at Johns Hopkins School of Medicine, or Medical trainee at Hopkins Hospital or Bayview Program

Exclusion criteria

• None

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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168 participants in 2 patient groups

CDC/NTCA guidelines only

Active Comparator group

Description:

The control group will have a link to US guidelines only and use it as a resource to answer the case vignettes.

Treatment:

Behavioral: CDC/NTCA guidelines only

LTBI ASSIST and CDC/NTCA guidelines

Experimental group

Description:

The intervention group will have a link to both US guidelines, and the LTBI-ASSIST tool as resources to answer the case vignettes.

Treatment:

Behavioral: LTBI ASSIST and CDC/NTCA guidelines only