Clinical Presentation and Outcome of COPD Patients With Acute Exacerbation Attending Sohag University Hospital

Sohag University

Status: Not yet enrolling

Conditions: Chronic Obstructive Pulmonary Disease

Study type: Observational

Funder types: Other

Identifiers

NCT06684353

Soh-Med-24-09-15MS

Details and patient eligibility

About

Chronic obstructive pulmonary disease (COPD) is a worldwide public health challenge because of high prevalence and related disability and mortality (1).

Acute exacerbation of COPD (AECOPD), defned as the worsening of respiratory symptoms and requirement of additional clinical treatment, it reduces lung function and quality of life, and is accompanied by an increased disease-related burden, high hospital mortality and poor outcome (2).

Chronic obstructive pulmonary disease frequently coexists with other chronic diseases, namely comorbidities. They negatively impact prognosis, exacerbations and quality of life in COPD patients. Local and systemic inflammation have been proposed as having a potential role in explaining the association between COPD and these comorbidities (3).

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

patients with a confirmed COPD diagnosis according to (GOLD) guidelines, presented with acute exacerbation

Exclusion criteria

• Stable COPD
• Any other chronic chest diseases; Bronchial asthma or bronchiectasis

Trial design

200 participants in 2 patient groups

COPD patients in ICU with high risk of mortality (non survivors)

Description:

COPD patients on NIV / MV

COPD patients in ICU with low risk of mortality ( survivors )

Description:

COPD patients on NIV / MV