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Clinical Presentation and Outcome of COPD Patients With Acute Exacerbation Attending Sohag University Hospital

S

Sohag University

Status

Not yet enrolling

Conditions

Chronic Obstructive Pulmonary Disease

Study type

Observational

Funder types

Other

Identifiers

NCT06684353
Soh-Med-24-09-15MS

Details and patient eligibility

About

Chronic obstructive pulmonary disease (COPD) is a worldwide public health challenge because of high prevalence and related disability and mortality (1).

Acute exacerbation of COPD (AECOPD), defned as the worsening of respiratory symptoms and requirement of additional clinical treatment, it reduces lung function and quality of life, and is accompanied by an increased disease-related burden, high hospital mortality and poor outcome (2).

Chronic obstructive pulmonary disease frequently coexists with other chronic diseases, namely comorbidities. They negatively impact prognosis, exacerbations and quality of life in COPD patients. Local and systemic inflammation have been proposed as having a potential role in explaining the association between COPD and these comorbidities (3).

Enrollment

200 estimated patients

Sex

All

Ages

18 to 90 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

patients with a confirmed COPD diagnosis according to (GOLD) guidelines, presented with acute exacerbation

Exclusion criteria

  • Stable COPD
  • Any other chronic chest diseases; Bronchial asthma or bronchiectasis

Trial design

200 participants in 2 patient groups

COPD patients in ICU with high risk of mortality (non survivors)
Description:
COPD patients on NIV / MV
COPD patients in ICU with low risk of mortality ( survivors )
Description:
COPD patients on NIV / MV

Trial contacts and locations

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Central trial contact

Hamdy A Mohammaden, Professor doctor; Mona A Hussien, Resident doctor

Data sourced from clinicaltrials.gov

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