Clinical Quality Improvement of Benzodiazepine-Resistant Alcohol Withdrawal Syndrome

University of Pittsburgh

Status: Completed

Conditions: Alcohol Withdrawal Syndrome

Treatments: Drug: Diazepam

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT01652326

UPittsburgh 0031860

Details and patient eligibility

About

The overarching goal of this project is to improve the clinical quality of patients with Benzodiazepine-resistant alcohol withdrawal syndrome.

Enrollment: 792 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

either

1. a requirement of either 200 mg of diazepam (or diazepam equivalents) in 4 hrs;
2. > 40mg of diazepam (or diazepam equivalents) in 1 hr; or
3. an individual dose of 40 mg or greater of intravenous diazepam for control of agitation

Exclusion criteria

• if < 18 years of age or had evidence of use of other illicit substances as determined by urine toxicology screen

Trial design

792 participants in 1 patient group

Benzodiazepine-resistant

Description:

those patients with either 1) a requirement of either 200 mg of diazepam (or diazepam equivalents) in 4 hrs; 2) \>40mg of diazepam (or diazepam equivalents) in 1 hr; or 3) an individual dose of 40 mg or greater of intravenous diazepam for control of agitation

Treatment:

Drug: Diazepam