Clinical-randomized Trial of the Effect of Rehabilitation Therapy Using Strength and Blood Flow Restriction Training on Muscular Fitness and Regeneration After Anterior Cruciate Ligament Reconstruction

University Hospital Bonn (UKB)

Status: Enrolling

Conditions: ACL - Anterior Cruciate Ligament Rupture

Treatments: Other: Resistance Training with Sham-BFR; Other: Resistance Exercise with BFR

Study type: Interventional

Funder types: Other

Identifiers

NCT07043569

2024_F

Details and patient eligibility

About

With the intention of improving rehabilitation after anterior cruciate ligament reconstruction, the present project investigates the influence of a targeted strength and blood flow restriction training intervention (BFR training) on the regeneration of muscle mass, strength and functionality of the knee joint. BFR training is characterized by the combination of external venous vascular occlusion with light strength training and still enables users to achieve gains in muscle mass and strength that are comparable to training with high mechanical loads. The positive effects of BFR training in the course of knee arthroplasty have already been demonstrated by our working group as a prehabilitative approach, i.e. as a training intervention prior to surgery. In the present project, the framework conditions of outpatient rehabilitation at the Bonn Center for Outpatient Rehabilitation will now be used to prove whether sports science-controlled strength and BFR training has a similar effect in the postoperative rehabilitation phase. The interventions are carried out as part of the exercise therapy units in outpatient rehabilitation ETM01 in accordance with the S2k guideline on anterior cruciate ligament rupture. Strength and BFR training in medical training therapy supplements the daily exercise therapy to ensure implementation in the rehabilitation process in line with the guidelines.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ACL reconstruction
• Ability to take part in an outpatient rehabilitation

Exclusion criteria

• Sickle Cell anemia
• iatrogenic changes in the vessels of the lower limbs (stents, bypasses)
• inflammation of the lower extremities

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 2 patient groups

Control Group

Active Comparator group

Description:

Control group will perform the exercise protocols with a sham-BFR pressure of 20 mmHg.

Treatment:

Other: Resistance Training with Sham-BFR

Intervention Group

Experimental group

Description:

Intervention group will perform the exercise protocols with a BFR pressure corresponding to 60% of the individual limb occlusion pressure.

Treatment:

Other: Resistance Exercise with BFR