Clinical Relevance of Anti-Neutrophil Cytoplasm Antibody (ANCA)in Hospitalized Patients

Hillel Yaffe Medical Center

Status: Unknown

Conditions: ANCA-related Vasculitis

Treatments: Other: Interpretation of blood test results

Study type: Observational

Funder types: Other

Identifiers

NCT01238003

HYMC-10-0087

Details and patient eligibility

About

Laboratory testing of Anti-Neutrophil Cytoplasm Antibody (ANCA) is used to confirm diagnosis of patients who have a high level of suspicion for ANCA-related vasculitis. In these patients the specificity and sensitivity to the ANCA test is very high. This study hopes to prove that when this lab test is performed on blood of patients who do not have a high level of suspicion for ANCA-related vasculitis, the sensitivity and specificity is reduced and there are many false positive results. Because of this, it should not be used as a screening test for a more general patient population.

Enrollment: 380 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Blood samples sent for ANCA lab test

Exclusion criteria

• Patients with ANCA vasculitis
• Patients with known malignancy

Trial design

380 participants in 1 patient group

Hospitalized patients

Treatment:

Other: Interpretation of blood test results