Clinical Relevance of Typing HLA-DR7-DQ2

Corporacion Parc Tauli

Status: Completed

Conditions: HLA-DQ2 Typing Include HLA-DR7-DQ2 Haplotypes; Celiac Disease Patients Following Recommendations of ESPGHAN

Treatments: Other: There is not any intervention

Study type: Observational

Funder types: Other

Identifiers

NCT01813383

Celiac disease and HLA-DQ2.2

Details and patient eligibility

About

Celiac disease patients with HLA-DR7-DQ2 haplotype have the same histological, analytical and clinical behaviour as patients with HLA-DR3-DQ2 haplotype.

Enrollment: 92 patients

Sex: All

Ages: Under 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of celiac disease following ESPGHAN recommendations
• HLA-DQ2 typing including HLA-DR3-DQ2 and HLA-DR7-DQ2 haplotypes

Exclusion criteria

• Patients who have not been diagnosed for celiac disease
• HLA-DQ2 typing that not include HLA-DR7-DQ2 haplotype

Trial design

92 participants in 2 patient groups

HLA-DR3-DQ2 patients

Description:

Patients with HLA-DR3-DQ2 haplotype

Treatment:

Other: There is not any intervention

HLA-DR7-DQ2 patients

Description:

Patients with HLA-DR7-DQ2 haplotype

Treatment:

Other: There is not any intervention