Clinical Research of H3F3AK27M in Spinal Glioma and Its Impact on TMZ Chemoradiotherapy

Southern Medical University

Status: Unknown

Conditions: Spinal Tumor

Treatments: Other: Genetic testing

Study type: Observational

Funder types: Other

Identifiers

NCT03668522

SouthernMUC Neurospine-1

Details and patient eligibility

About

H3F3AK27M may be a feature of primary spinal cord glioma and affect the outcome and prognosis of TMZ chemoradiotherapy.

Enrollment: 60 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Surgical treatment and pathological confirmation of spinal glioma in our department and is the first case without any treatment before operation.

Exclusion criteria

• The tumor is recurrent or has been treated before operation.

Trial design

60 participants in 2 patient groups

children

Description:

age\<=17

Treatment:

Other: Genetic testing

adult

Description:

age\>17

Treatment:

Other: Genetic testing