Clinical Research to Explore Manifestations of Heart Failure Using Infrared Thermal Imaging Technology

Jing Huang

Status: Unknown

Conditions: Heart Failure，Congestive

Study type: Observational

Funder types: Other

Identifiers

NCT02672618

JHuang

Details and patient eligibility

About

The purpose of this study is to explore manifestations of Heart Failure Using Infrared Thermal Imaging Technology.

Full description

Temperature is a vital and useful indicator for various diseases.Infrared thermal imaging (IRTI) allows the temperature representation of the body surface by thermal distribution, where it depends on the complex relationships defining the heat exchange processes between skin tissue, inner tissue, local vasculature, and metabolic activity.

The decrease in cardiac output in heart failure activate a series of compensatory adaption that are intended to maintain cardiovascular homeostasis. One of most important adaptation is activation of sympathetic nervous system, which could cause peripheral cutaneous vasoconstriction and decrease the skim temperature. Hence, the skim temperature of heart failure would be lower than health people,but which could not discovery by eye. The investigators hypothesize that IRTI could evaluate heart failure by the imaging of temperature distribution in the face on early stages.The aim of this study is to determine the effectiveness of infrared thermal imaging in evaluating heart failure.

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Willing to participate in the trial and sign the informed consent form
2. Aged: 18-85 years
3. Was diagnosed as heart failure
4. There is no trauma, infection, biopsy or puncture, hemorrhage and tumor in the corresponding detection site (face)
5. There is no skin disease, heart, liver, kidney, gastrointestinal tract, hematopoietic system and mental, neurological has no serious diseases

Exclusion criteria

1. Fever causes by any reasons, temperature higher than 37.4℃
2. Infection
3. Renal failure
4. Cerebrovascular diseases
5. Moderate anemia or more
6. Not willing to participate in clinical trials

Trial design

200 participants in 3 patient groups

chronic heart failure

Description:

18-85years old,having symptoms of heart failure,New York Heart Association（NYHA） class II or above American College of Cardiology/American Heart Association（ACC/AHA） class B, C, including hypertensive heart disease, rheumatic heart disease, ischemic cardiomyopathy and idiopathic cardiomyopathy

normalCardiac function

Description:

18-85years old,no symptoms of heart failure,NYHA class I or above ACC/AHA class A, including controled hypertension,stability coronary heart disease and rheumatic heart disease

healthy volunteers

Description:

18-85years old,Without basic cardiovascular diseases