Clinical Significance of Detecting CEA and CK20 mRNA-positive Cells in Colorectal Cancer Patients

The Institute of Molecular and Translational Medicine, Czech Republic

Status: Completed

Conditions: Circulating Tumor Cell; Colorectal Cancer

Treatments: Device: CTC/DTC count

Study type: Interventional

Funder types: Other

Identifiers

NCT03337347

CTC_CRC_2017

Details and patient eligibility

About

To determine whether the presence of circulating/disseminated tumor cells (CTCs/DTCs) in the blood and bone marrow of colorectal cancer (CRC) patients with localized disease is a negative prognostic factor, and to find correlations with other clinical/pathological disease characteristics.

Enrollment: 256 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• colorectal adenocarcinoma

Exclusion criteria

• prior neoadjuvant chemoradiotherapy
• prior colorectal cancer
• cancer duplicity

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)