Clinical Significance of Marginal Acute Inflammation for Stage II Colon Cancer

Sun Yat-sen University

Status: Completed

Conditions: Inflammation; Colon Cancer

Treatments: Diagnostic Test: MAI detection

Study type: Observational

Funder types: Other

Identifiers

NCT06135558

GIH-SYip32

Details and patient eligibility

About

Marginal acute inflammation would make reporting the serosal involvement of tumors controversial. We aimed to investigate the clinical significance and explore the prognostic value of MAI for stage II localized colon cancer.

Enrollment: 1,167 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• (1) colon cancer patients with the preoperative staging of stage I-III who lacked distant metastasis; (2) patients who underwent radical resection, with postoperative pathology confirmed as pT3-4N0M0; and (3) complete follow-up information

Exclusion criteria

• (1) patients who received neo-adjuvant therapy; (2) patients with multiple primary colorectal cancer; and (3) patients with a history of malignant tumors

Trial design

1,167 participants in 3 patient groups

T3

Description:

patient staged T3 without marginal acute inflammation

Treatment:

Diagnostic Test: MAI detection

MAI

Description:

patient with marginal acute inflammation

Treatment:

Diagnostic Test: MAI detection

T4

Description:

patient staged T4 without marginal acute inflammation

Treatment:

Diagnostic Test: MAI detection