Clinical Study of Depodur Efficacy in Decreasing Post Operative Pain After Off Pump Coronary Artery Bypass Grafting (OP-CABG)
Status
Conditions
Treatments
Details and patient eligibility
About
The purpose of this study is to determine whether epidural Depodur alleviates the pain of OP-CABG surgery. This includes pain associated with sternotomy, retraction, dissection and other tissue insults, as well as the induced inflammatory system and effects from prolonged ventilation in the ICU setting.
Full description
The purpose of this study is to determine whether epidural Depodur alleviates the pain of OP-CABG surgery. This includes pain associated with sternotomy, retraction, dissection and other tissue insults, as well as the induced inflammatory system and effects from prolonged ventilation in the ICU setting. It will be compared to placebo.
Sex
Ages
Volunteers
Inclusion criteria
- Male or Female, 18-99 years old
- All patients who will have surgery for OP-CABG
Exclusion criteria
- Pregnant females
- Patients with allergy to morphine
- Patients nursing an infant
- Patients with migraine headaches
- Patients taking Coumadin within 7 days or demonstrating INR > 13
- Patients taking Heparin unless documented normal partial thromboplastin time
- Patients taking Clopidogrel in previous 7 days
- Patients taking Ticlopidine in previous 14 days
- Patients taking Aspirin in previous 48 hours
- Patients receiving low molecular weight heparin therapy within 24 hours previous
- Patients with Narcolepsy and/or sleep apnea
- Patients on chronic opioid therapy
- Patients participating in another study
Trial design
Primary purpose
Allocation
Interventional model
Masking
0 participants in 2 patient groups
Trial contacts and locations
Loading...
Data sourced from clinicaltrials.gov
Clinical trials
Research sites
Resources
Legal