Clinical Study of Targeted Cryoablation Therapy in the Treatment of Hepatic Carcinoma

Shanghai University of Traditional Chinese Medicine

Status and phase: Unknown; Phase 2

Conditions: Liver Neoplasms

Treatments: Procedure: Targeted Cryoablation Therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT02969096

AAAA

Details and patient eligibility

About

The purpose of this study is to evaluate the safety and efficacy of targeted cryoablation therapy for hepatic carcinoma.

Full description

A cryoprobe is inserted percutaneously under CT guidance into the targeted lesion. Patients undergo ablation using a freeze-thaw-freeze cycle lasting approximately 10-6-10minutes.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of liver cancer based on histology or the current accepted radiological measures.
• Single Tumor size ≤5.0 cm in greatest diameter, or multiple tumor number≤3 and each tumor size≤ 3cm.
• Life expectancy: Greater than 3 months.
• Patients' liver function is Child-pugh A or B.
• Ability to understand the study protocol and a willingness to sign a written informed consent document.
• Unable to receive operative surgery.

Exclusion criteria

• Patients with other primary tumor except liver cancer.
• History of coagulation disorders or anemia.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

Targeted Cryoablation Therapy

Experimental group

Description:

liver cancer patients received targeted cryoablation therapy.

Treatment:

Procedure: Targeted Cryoablation Therapy