Clinical Study on Laparoscopic Resection of Splenic Artery Aneurysm With Preservation of Spleen

Northern Jiangsu People's Hospital

Status: Enrolling

Conditions: Immune Function; Splenic Artery Aneurysm; Hemodynamics

Treatments: Procedure: laparoscopic resection of splenic artery aneurysm with preservation of spleen

Study type: Interventional

Funder types: Other

Identifiers

NCT07053605

YZUC-013

Details and patient eligibility

About

In this study, researchers examined the changes in related indicators such as immune function, splenic vein,proper hepatic artery, and portal venous hemodynamics following laparoscopic resection of a splenic artery aneurysm. We determined the changes in these patient-related indicators after surgical treatment and whether these changes could improve patient outcomes.

Full description

Patients with Splenic Artery Aneurysm were recruited in accordance with the research inclusion criteria, and their general demographic information was collected. After thorough preoperative preparation, the same surgical team performed laparoscopic resection of the splenic artery aneurysm. Postoperatively,the same nursing team provided standardized care. Subsequently, patients received a standardized postoperative treatment protocol, which included pharmacotherapy, additional therapeutic interventions, and follow-up visits. During the treatment period, routine blood tests,liver function tests, coagulation function,immune function, as well as the hemodynamics of the portal vein, proper hepatic artery, and splenic vein were monitored preoperatively and at 7 days, 1 month, 3 months, 6 months, and 12 months postoperatively.

Enrollment: 10 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Asymptomatic splenic artery aneurysms with a diameter>2 cm,ruptured splenic artery aneurysms,and splenic artery aneurysms with a diameter increase>0.5 cm/year.

Aneurysm located in the main trunk of the splenic artery. Informed consent to participate in the study.

Exclusion criteria

• Patients with malignancies Hepatic cirrhosis with portal hypertension peptic ulcer disease Recent peptic ulcer disease History of Hemorrhagic stroke Pregnancy hematological diseases Uncontrolled Hypertension Human immunodeficiency virus (HIV) infection

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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10 participants in 1 patient group

The laparoscopic resection of splenic artery aneurysm is performed by the same surgical team.

Experimental group

Description:

The laparoscopic resection of splenic artery aneurysm with preservation of spleen is performed by the same surgical team.

Treatment:

Procedure: laparoscopic resection of splenic artery aneurysm with preservation of spleen