Correlation Between Perioperative EEG Variability and Postoperative Delirium Incidence.

Xin Chen

Status: Enrolling

Conditions: Delirium - Postoperative

Treatments: Device: Collect preoperative and intraoperative electroencephalogram data

Study type: Observational

Funder types: Other

Identifiers

NCT07323940

No.823RC592 (Other Identifier)

HUMU2H-EEGAMSE-CN-2025

Details and patient eligibility

About

This clinical study aims to investigate whether multiscale entropy analysis of electroencephalogram data can distinguish between ordinary elderly surgical patients and elderly patients with postoperative delirium.This study may help identify postoperative delirium in surgical patients at an early stage.

Enrollment: 90 estimated patients

Sex: All

Ages: 65+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Patients undergoing general anaesthesia with single-lumen endotracheal tube placement;
2. Age ≥65 years, gender unrestricted, body mass index (BMI) 18-28 kg/m²;
3. Normal mouth opening and head/neck mobility;
4. Pre-anaesthesia American Society of Anaesthesiologists (ASA) physical status classification of I or II and Mallampati airway classification of I or II.

Exclusion criteria

1. Individuals with psychiatric disorders, literacy issues, or communication difficulties who are unable to cooperate with POD screening;
2. Patients with severe lesions in vital organs, such as the heart, lungs, brain, liver or kidneys.
3. Those undergoing cardiac or neurosurgical procedures during this admission;
4. A history of alcohol abuse or recent use of sedatives or opioids;
5. haemoglobin <100 g/L;
6. Participation in any clinical research studies within the past 3 months.

Trial design

90 participants in 1 patient group

Elderly surgical patients undergoing general anaesthesia.

Treatment:

Device: Collect preoperative and intraoperative electroencephalogram data