Clinical Trial of CBASP for Individuals With Co-occurring Chronic Depression and Alcohol Dependence

University of Virginia

Status: Completed

Conditions: Alcoholism; Major Depressive Disorder; Dysthymic Disorder; Depressive Disorder; Alcohol-Related Disorders

Treatments: Behavioral: Cognitive Behavioral Analysis System of Psychotherapy

Study type: Observational

Funder types: Other

Identifiers

NCT01528748

15599

Details and patient eligibility

About

This study examines the effectiveness of Cognitive Behavioral Analysis System of Psychotherapy (CBASP) in reducing both alcohol consumption and depressive symptoms in adults who are chronically depressed and alcohol dependent.

Full description

This study examines the effectiveness of Cognitive Behavioral Analysis System of Psychotherapy (CBASP) in reducing both alcohol consumption and depressive symptoms in adults who are chronically depressed and alcohol dependent. Participants will receive a 20-session course of CBASP psychotherapy over a period of 21 weeks and will be assessed for severity of pretreatment psychological abuse and trauma as well as pre and posttreatment interpersonal functioning. Two primary hypotheses are to be tested: 1) demonstrate that CBASP is effective in reducing depressive symptoms (Hamilton Rating Scale for Depression-24 ratings) and alcohol consumption (drinks per drinking day) in this chronically depressed alcohol dependent cohort when posttreatment ratings are compared to pretreatment levels; and 2) demonstrate that acquisition of feeling safe with the therapist and acquisition of the ability to perceive the interpersonal consequences of one's behavior will significantly increase from pre to posttreatment levels and will be associated with reductions in drinking and depressive symptoms.

Enrollment: 8 patients

Sex: All

Ages: 21 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of a current major depressive disorder (e.g., Major Depression, Dysthymic Disorder) for a minimum of two years
• Clinical diagnosis of alcohol dependence during the last thirty days
• Interest in changing one's drinking and alleviating depressive symptoms

Exclusion criteria

• Please call study site for additional information

Trial design

8 participants in 1 patient group

Chronically Depressed, Alcohol Dependent

Description:

Participants who have been formally diagnosed with a clinical diagnosis of Chronic Depression and Alcohol Dependence.

Treatment:

Behavioral: Cognitive Behavioral Analysis System of Psychotherapy