Clinical Trial of Lupeol for Mild-moderate Acne

Seoul National University

Status: Completed

Conditions: Acne

Treatments: Drug: Control vehicle; Drug: Lupeol

Study type: Interventional

Funder types: Other

Identifiers

NCT02152865

anti-acne product

Details and patient eligibility

About

For the chemical lupeol isolated from eggplant, we applied it to one side of face, and applied vehicle control to another side for 8 -weeks. The study was performed in a 8-week, randomized controlled, split face fashion. Investigators evaluated safety and efficacy during baseline, 2 weeks, 4weeks, and 8 weeks after beginning of study.

Enrollment: 25 patients

Sex: All

Ages: 15+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients over the age 15 who were clinically diagnosed with mild to moderate acne vulgaris

Exclusion criteria

• ; known pregnancy or lactation, any medical illness that might influence the results of the study, a previous history of oral acne medication or surgical procedures including laser treatment within 6 month and topical medication within 4 weeks of study enrollment.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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25 participants in 2 patient groups, including a placebo group

Lupeol

Active Comparator group

Description:

Patients are supposed to apply lupeol on one side of face two times per day for 8 weeks

Treatment:

Drug: Lupeol

Control vehicle

Placebo Comparator group

Description:

Patients are supposed to apply vehicle control to another side of face two times per day for 8 weeks

Treatment:

Drug: Control vehicle