Clinical Trial to Compare the Efficacy of a Fluoride Gel and a Dental Bonding Agent in Treatment of Tooth Sensitivity

University of Kent

Status: Completed

Conditions: Dentin Sensitivity

Treatments: Procedure: Self-etching Dentine Bonding Agent; Procedure: Colgate Fluoride Varnish Suspension. 2.26% Sodium Fluoride.

Study type: Interventional

Funder types: Other

Identifiers

NCT02919202

ResGov 354

Details and patient eligibility

About

This study compares the efficacy of two dental interventions in the treatment of cervical dentine sensitivity. The participants will be selected from adult dental patients registered at a general dental practice in West Sussex, UK. The participants will be split into 2 groups. One group will receive the intervention of topical fluoride varnish application while the other group will receive a topical application of self-etching dentine bonding agent.

Full description

Topical Fluoride Varnish(TFV) and Self-Etching Dentine Bonding Agent (SEDBA) are both routinely used in dentistry in the management of cervical dentine sensitivity(CDS). Both interventions are topically applied and well tolerated by patients. The interventions differ in mechanism of action. TFV releases fluoride which is incorporated into the organic matrix of dentine making the dentine tubules less conductive. Dentinal tubules form the key conduit between stimulus and pain perception in the tooth. SEDBA differs in that it penetrates and occludes the tubules. It is light cured for an almost instant set time.

Enrollment: 26 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Aged 18-60.
• Exhibiting CDS elicited by the two test stimuli in relation at least one tooth.

Exclusion criteria

• Patients who have undergone comprehensive periodontal treatment in the past 3 months.
• Patients under the age of 18 or unable to provide valid consent.
• Teeth that have visible fracture lines, caries, crowns or have been endodontically treated.
• Patients taking analgesic medication for any systemic conditions.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

26 participants in 2 patient groups

Fluoride Varnish

Experimental group

Description:

Colgate Fluoride Varnish Suspension. 2.26% Sodium Fluoride.

Treatment:

Procedure: Colgate Fluoride Varnish Suspension. 2.26% Sodium Fluoride.

SEDBA

Active Comparator group

Description:

Self-etching Dentine Bonding Agent. Scotchbond Universal by 3M ESPE. Topical application followed by light curing for 20 seconds.

Treatment:

Procedure: Self-etching Dentine Bonding Agent