Clinical Usefulness of Virtual Ablation Guided Catheter Ablation of Atrial Fibrillation: Prospective Randomized Study

Yonsei University

Status: Completed

Conditions: Atrial Fibrillation

Treatments: Procedure: conventional ablation based on physician's personal experience; Procedure: Virtual ablation in based 3D CT of patient who diagnosed AF

Study type: Interventional

Funder types: Other

Identifiers

NCT02171364

4-2013-0536

Details and patient eligibility

About

Radiofrequency catheter ablation is highly effective in the treatment of patients with persistent atrial fibrillation. In order to decrease the recurrence rate after catheter ablation, the investigators propose to apply 'virtual' ablation on patient-specific atria by simulating 3D atrial computer model. The investigators will test with five different set of ablation methods and find successful methods for a specific patient. Then, this result will be compared to empirical catheter ablation result by randomly controlled trial.

Enrollment: 40 patients

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of AF patients who performed catheter ablation of atrial fibrillation due to uncontrolled pulse rate by anti-arrhythmic drug therapy.

Exclusion criteria

• AF patients who have severe heart deformations or blood problems.
• The patients who had been performed catheter ablation of atrial ablation.
• The patients who missed out to recording of 3D CT, echo and electrocardiography.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

virtual simulation

Experimental group

Description:

This intervention group is to choose the best effective method operation to patients by simulating 3D atrial computer model which consider patient's heart size and shape.

Treatment:

Procedure: Virtual ablation in based 3D CT of patient who diagnosed AF

conventional ablation

Active Comparator group

Description:

The other intervention group is to operate the atrial fibrillation by physician's personal experience, not by virtual simulation.

Treatment:

Procedure: conventional ablation based on physician's personal experience