Clinical Utility of Intraoperative Parathyroid Scores System in Thyroidectomy (IPSS)

Fujian Medical University

Status: Completed

Conditions: Intraoperative Parathyroid Scores System

Treatments: Procedure: Different range of thyroid surgery

Study type: Observational

Funder types: Other

Identifiers

NCT03172312

IPSSforZHAO

Details and patient eligibility

About

Ready to establish the Intraoperative Parathyroid Scores System (IPSS) for thyroidectomy and study the clinical value of Intraoperative Parathyroid Scores System for thyroidectomy.

Full description

IPSS includes transplantation Parathyroid Scores and in situ Parathyroid Scores, the investigators will establish the Intraoperative Parathyroid Scores System by parathyroid size and Blood supply, and recording IPSS, according to certain rules. Parathyroid hormone and calcium were test in d0, d1, d14, d60 post operation. The correlation between Intraoperative Parathyroid Scores and PTH calcium were calculated, and ROC curve and logistic regression were tested for the prediction value.

Enrollment: 500 patients

Sex: All

Ages: Under 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. postoperative pathology confirmed as thyroid papillary carcinoma;
2. for the first time to undergo thyroid surgery, no history of neck surgery and external radiotherapy;
3. preoperative serum calcium, parathyroid hormone levels were normal;
4. intraoperative and postoperative clinical data integrity, standardized follow-up patients;
5. parathyroid is a tumor violation.

Exclusion criteria

1. serious underlying disease;
2. age greater than 60 years of age or combined with arteriosclerotic disease;
3. patients with postoperative loss;
4. patients with parathyroid disease.

Trial design

500 participants in 2 patient groups

Total thyroidectomy

Description:

Patients need to do total thyroidectomy According to guidelines

Treatment:

Procedure: Different range of thyroid surgery

Hemithyroidectomy

Description:

Patients need to do Hemithyroidectomy According to guidelines

Treatment:

Procedure: Different range of thyroid surgery