Clinical Utility of the 1-minute Sit to Stand Test as a Measure of Submaximal Exercise Tolerance in Patients With Cystic Fibrosis During Acute Pulmonary Exacerbation

Boston Children's Hospital

Status

Completed

Conditions

Cystic Fibrosis

Treatments

Diagnostic Test: Sit to stand test

Study type

Interventional

Funder types

Other

Identifiers

NCT04058548

IRB-P00031139

Details and patient eligibility

About

The aim of this study is to assess whether the 1 minute Sit to Stand (STS) test can be used as a measure of submaximal endurance during a pulmonary exacerbation of Cystic Fibrosis (CF) for patients in the acute care setting. We hypothesize that if the STS test is a valid measure of submaximal cardiovascular endurance, it will moderately correlate with 6 minute walk distance (6MWD).

Enrollment

27 patients

Sex

All

Ages

6 to 35 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

patients age 6-35 with cystic fibrosis who are admitted for a pulmonary exacerbation and receive ongoing physical therapy throughout their admission.

Exclusion criteria

patients with cystic fibrosis who are under the age of 6,
patients with cystic fibrosis who are not admitted for a pulmonary exacerbation,
patients with cystic fibrosis who are not being followed regularly by physical therapy (>5x/week) throughout their inpatient admission,
patients with cystic fibrosis who are unable to follow instructions for standardized testing,
patients with cystic fibrosis who are not medically stable to participate in submaximal exercise testing.
patients whose inpatient admission is anticipated to be <1 week.
Patients who are readmitted to the hospital within the year will not be included in the study more than once.