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Clinical Validation of Machine Learning Triage of Chest Radiographs

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Stanford University

Status

Withdrawn

Conditions

Chest--Diseases

Treatments

Other: Traditional workflow triage
Other: Machine learning workflow triage
Other: Random workflow triage

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

Artificial intelligence and machine learning have the potential to transform the practice of radiology, but real-world application of machine learning algorithms in clinical settings has been limited. An area in which machine learning could be applied to radiology is through the prioritization of unread studies in a radiologist's worklist. This project proposes a framework for integration and clinical validation of a machine learning algorithm that can accurately distinguish between normal and abnormal chest radiographs. Machine learning triage will be compared with traditional methods of study triage in a prospective controlled clinical trial. The investigators hypothesize that machine learning classification and prioritization of studies will result in quicker interpretation of abnormal studies. This has the potential to reduce time to initiation of appropriate clinical management in patients with critical findings. This project aims to provide a thoughtful and reproducible framework for bringing machine learning into clinical practice, potentially benefiting other areas of radiology and medicine more broadly.

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Radiologist at Stanford Hospital and Clinics

Exclusion criteria

  • None

Trial design

Primary purpose

Diagnostic

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Single Blind

0 participants in 3 patient groups

Traditional workflow triage
Active Comparator group
Description:
Radiologists follow standard triage of chest radiographs.
Treatment:
Other: Machine learning workflow triage
Other: Traditional workflow triage
Other: Random workflow triage
Machine learning workflow triage
Active Comparator group
Description:
Radiologists follow machine learning triage of chest radiographs.
Treatment:
Other: Machine learning workflow triage
Other: Traditional workflow triage
Other: Random workflow triage
Random workflow triage
Sham Comparator group
Description:
Radiologists follow randomly ordered triage of chest radiographs.
Treatment:
Other: Machine learning workflow triage
Other: Traditional workflow triage
Other: Random workflow triage

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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