Clinical Value of Molecular Genetic Analyzes in Gynecological Malignomas (MAGynMA)

University Hospital Tuebingen

Status: Completed

Conditions: Gynecologic Cancer

Treatments: Diagnostic Test: molecular genetic analyses

Study type: Observational

Funder types: Other

Identifiers

NCT03194347

MAGynMA

Details and patient eligibility

About

The aim of the planned research project is to find out the clinical significance of molecular genetic analyzes in gynecological malignomas. In particular, it will be investigated how the knowledge of a molecular-genetic finding affects the therapeutic decision of the physician. Furthermore, genetic changes in the tumor tissue will be compared with the changes in CTCs, DTCs and cfDNA.

Enrollment: 300 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with a solid tumor disease
• The presence of a molecular genetic diagnosis of the tumor tissue from practice for human genetics
• Age > 18 years
• informed consent

Exclusion criteria

• life expectancy <12 months or worse general condition (Karnofsky <70)