Clinician Managed Interpersonal Psychotherapy

University of Iowa

Status and phase: Completed; Early Phase 1

Conditions: Depression, Postpartum; Depression

Treatments: Behavioral: Standard interpersonal psychotherapy (IPT); Behavioral: Clinician managed interpersonal psychotherapy (CM-IPT)

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT00043602

DSIR 83-ATAS

R01MH059668 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This 12-week study will evaluate the effectiveness of Clinician-Managed Interpersonal Psychotherapy (CM-IPT) in treating postpartum depression and will compare CM-IPT to standard IPT.

Full description

CM-IPT is delivered in 12 sessions over the course of a year. Standard IPT is delivered in 12 sessions in the first 12 weeks after treatment assignment.

Enrollment: 140 patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Women between 8 and 24 weeks postpartum
• Meet DSM-IV criteria for Major Depression
• Hamilton Rating Scale for Depression score of 12 or more

Exclusion criteria

• Active substance abuse
• Psychotic disorders

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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140 participants in 2 patient groups

1

Experimental group

Description:

Participants will receive clinician-managed interpersonal psychotherapy

Treatment:

Behavioral: Clinician managed interpersonal psychotherapy (CM-IPT)

2

Active Comparator group

Description:

Participants will receive standard interpersonal psychotherapy

Treatment:

Behavioral: Standard interpersonal psychotherapy (IPT)