Clinico-biological Characterization and Survival of Patients With Adult T-cell Leukemia / Lymphoma (ATL) and Patients Chronically Infected With the HTLV-1 Virus (HTLV-OBS)

Assistance Publique - Hôpitaux de Paris

Status: Enrolling

Conditions: Lymphoproliferation Induced by HTLV-1; HTLV-1 Adult T-cell Lymphoma / Leukemia; HTLV-1 Infection

Study type: Observational

Funder types: Other

Identifiers

NCT05237245

2020-A02320-39 (Other Identifier)

APHP180684

Details and patient eligibility

About

The purpose of this study is to evaluate the outcome (survival) of Adult T-cell leukemia / lymphoma (ATL) patients who receive or not specific treatment for their hemopathy (cohort 1) and the outcome (survival) of HTLV-1 chronically infected patients with / without extra-haematological disorders (cohort 2).

Enrollment: 120 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• 18 years old or older
• HTLV-1 infected
• T lymphoproliferation induced by HTLV-1 (cohort 1)
• without T lymphoproliferation induced by HTLV-1 (cohort 2)
• informed and accepted the collection of data

Exclusion Criteria

- Patients refusal of participation

Trial design

120 participants in 2 patient groups

1

Description:

Adult T-cell leukemia / lymphoma (ATL) patients

2

Description:

HTLV-1 chronically infected patients without ATL