Clip and Coil in Fundal Gastric Varices With a Large Shunt

Zhejiang University

Status: Completed

Conditions: Titanium Clips; Fundal Gastric Varices; Ectopic Embolization; Endoscopic Ultrasound (EUS)-Guided Coil Deployment; Gastric Variceal Pressure

Study type: Observational

Funder types: Other

Identifiers

NCT07263503

2025-1588

Details and patient eligibility

About

Endoscopic ultrasound (EUS)-guided coil deployment is a promising technique for the endoscopic management of gastric varices. However, coil migration may occur in patients with large drainage collaterals. This study aimed to evaluate the safety and efficacy of using clips in combination with coils for treating gastric varices. In this retrospective study, clips were placed before EUS-guided coil deployment in each patient with gastric varices and a large spontaneous portosystemic shunt. The pressure of gastric varices was directly measured by puncturing the varix with a needle connected to a pressure transducer, before and after clip placement. The occurrence of ectopic embolization or coil migration was recorded.

Enrollment: 31 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

1. presence of a spontaneous portosystemic shunt, including gastrorenal or splenorenal collateral shunts;
2. use of both clips and coils during endoscopic intervention.

Exclusion criteria

The spontaneous portosystemic shunt was narrow (diameter < 1.0 cm).

Trial design

31 participants in 1 patient group

Fundal gastric varices associated with a large spontaneous portosystemic shunt (>1cm)

Description:

Clips were placed before EUS-guided coil deployment