ClinicalTrials.Veeva

Menu

Clonidine in Femoral Nerve Block Surgery in Children

Nationwide Children's Hospital logo

Nationwide Children's Hospital

Status and phase

Withdrawn
Phase 2

Conditions

Other Reconstructive Surgery

Treatments

Drug: Clonidine
Drug: Ropivacaine

Study type

Interventional

Funder types

Other

Identifiers

NCT01293149
IRB11-00075

Details and patient eligibility

About

Knee arthroscopy is a common surgical procedure in pediatrics in which the knee joint is visualized through a small camera to help diagnose and treat knee problems. This procedure is commonly accomplished with the use of general anesthesia. Regional anesthesia is commonly completed with a single injection of local anesthetic around the femoral nerve to provide pain relief for several hours following knee arthroscopy. The intent of this study is to examine the effects of clonidine in addition to local anesthetics for femoral nerve blockade in providing children and adolescents post-operative analgesia. The investigators hypothesize the addition of low dose clonidine (1 mcg/kg) provides an additional 4 hours of post operative analgesia following arthroscopic knee surgery and reduces post-operative opiate requirement.

Sex

All

Ages

Under 21 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • American Society of Anesthesiologist (ASA) functional status I or II
  • Patients scheduled for arthroscopic knee surgery only

Exclusion criteria

  • Patients with history of chronic opioid therapy, central or peripheral neuropathy, contraindications to regional anesthesia, history of allergy to clonidine or ropivicaine, or anterior cruciate ligament reconstructive surgery in addition to knee arthroscopy

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Quadruple Blind

0 participants in 2 patient groups

Ropivacaine plus clonidine
Experimental group
Description:
Ropivacaine plus clonidine for femoral block
Treatment:
Drug: Clonidine
Ropivacaine
Active Comparator group
Description:
Ropivacaine alone for femoral block
Treatment:
Drug: Ropivacaine

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems