Closed Loop Ventilation Strategy in Intensive Care Unit (ICU) Patients

Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital

Status and phase: Completed; Phase 4

Conditions: Respiratory Failure; All Intubated Patients

Treatments: Device: Adaptive Support Ventilation; Device: Pressure Controlled Ventilation

Study type: Interventional

Funder types: Other

Identifiers

NCT01472302

IGCEAH-ICU 2

Details and patient eligibility

About

Adaptive support ventilation (ASV) is a closed loop ventilation mode that can act both like PCV and PSV automatically. Some studies suggest that ASV can reduce the weaning time in ICU patients. The investigators hypothesized that using ASV from the beginning of intubation can reduce the total duration of MV and LOS in the ICU when compared to conventional modes such as PCV+PSV

Enrollment: 229 patients

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Intubated and mechanically ventilated ICU patients for more than 24 hours

Exclusion criteria

• Patient with a tracheostomy
• Patients under home mechanical ventilation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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229 participants in 2 patient groups

ASV

Experimental group

Description:

Adaptive Support Ventilation

Treatment:

Device: Adaptive Support Ventilation

PCV

Active Comparator group

Description:

Pressure Controlled Ventilation

Treatment:

Device: Pressure Controlled Ventilation