Closure Techniques and Scar Appearance

Northwestern University

Status: Withdrawn

Conditions: Wound Closure Techniques

Treatments: Procedure: Subcuticular polyglactin-910 combined with tissue adhesive; Procedure: Running polypropylene closure; Procedure: Tissue Adhesive (Derma-Bond)

Study type: Interventional

Funder types: Other

Identifiers

NCT01352533

STU38040

Details and patient eligibility

About

The goal of this study is to assess whether wound closure with skin adhesive or running stitches combined with skin adhesive will be superior to standard wound sutures. This is a split-wound study that will compare two methods of skin closure within one standard closure technique, thereby providing an internal control of running stitches within each wound. The investigators plan to measure outcomes by assessing for scar appearance, the incidence of wound opening, scar elasticity and subject satisfaction.

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age 18 and over
• Linear closures on the head and neck, at least 3cm in length
• The subjects are in good health
• The subject has the willingness and the ability to understand and provide informed consent for the use of their tissue and communicate with the investigator.

Exclusion criteria

• Under 18 years of age
• Pregnancy or Lactation
• Subjects who are unable to understand the protocol or to give informed consent
• Subjects with mental illness
• Defects on the scalp

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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0 participants in 3 patient groups

Running polypropylene closure

Active Comparator group

Description:

Half of every linear wound will be closed with running polypropylene sutures. This technique is Standard of Care.

Treatment:

Procedure: Running polypropylene closure

Tissue Adhesive (Derma-Bond)

Experimental group

Description:

The experimental half of the wound will be randomized to receive closure with tissue adhesive alone.

Treatment:

Procedure: Tissue Adhesive (Derma-Bond)

Subcuticular polyglactin-910 combined with tissue adhesive

Experimental group

Description:

The experimental half of the wound will be randomized to receive closure with running subcuticular polyglactin-910 combined with tissue adhesive.

Treatment:

Procedure: Subcuticular polyglactin-910 combined with tissue adhesive