CMR-derived Quantitative Perfusion for Prediction of FFR

Kerckhoff Klinik

Status: Not yet enrolling

Conditions: Chronic Coronary Syndrome

Study type: Observational

Funder types: Other

Identifiers

NCT07018778

AZ 107/24

Details and patient eligibility

About

Patients will undergo quantitative perfusion assessment in cardiovascular magnetic resonance imaging (dual bolus or dual sequence approach) as well as invasive coronary angiography for assessment of fractional flow reserve (FFR) including assessment of coronary flow reserve (CFR) and microcirculatory resistance (IMR).

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• clinical indication for vasodilatator CMR or invasive coronar angiography
• capability to give informed consent

Exclusion criteria

• general: non-compliance, <18 years of age, pregnancy
• contraindications for CMR (non-CMR compatible device, chronic kidney disease (eGFR <30ml/min), allergies (medications)

Trial design

200 participants in 1 patient group

CCS patients

Description:

Clinical patients referred for ischaemia testing (CMR/coronary angiogram) will undergo the respective counterpart as well so that patients will have undergone both CMR and invasive testing.